SOX10 Rabbit Polyclonal Antibody
| Cat Number: | AB-84777 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to a sequence in the middle region of human SOX10, which shares 97.1% amino acid (aa) sequence identity with both mouse and rat SOX10. |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blot, 0.1-0.5ug/ml Flow Cytometry, 1-3ug/1x106 cells |
| Molecular Weight: | 60kDa |
| Synonyms: | Lyophilized |
| Background: | Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX (SRY-related HMGbox) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg- Shah and Waardenburg-Hirschsprung disease. |
| Form: | Lyophilized |
| Buffer: | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Storage: | Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |