SOX2 Rabbit Monoclonal Antibody
| Cat Number: | MABN86245 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human SOX2 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:200,FC 1:500-1:1000 |
| Molecular: | 37 kDa |
| Purification: | Affinity purification |
| Synonyms: | ANOP3; MCOPS3; Transcription factor SOX-2 |
| Background: | This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008] |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Western blot analysis of extracts from MCF-7 cells using SOX2 Rabbit Monoclonal Antibody at 1:100.