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Sp1 (I18)

Cat Number: AB-10269
Size: 200 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A synthesized peptide derived from human SP1.
Reactivity: Ms, Rt, Hu
Applications: Western Blot: 1:500 - 1:2000 Immunohistochemistry: 1:50 - 1:200 Immunofluorescence: 1:50 - 1:200
Molecular Weight: 90kDa
Purification: Aff. Pur.
Background:

The protein encoded by this gene is a zinc finger transcription factor that binds to GCrich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Form: Liquid
Buffer: PBS with 0.02% sodium azide, 0.05% BSA,50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.