SynGAP Rabbit Polyclonal Antibody
| Cat Number: | ABN00282 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human SynGAP |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100 |
| Molecular: | Calculated MW: 148 kDa; Observed MW: 148 kDa |
| Purification: | Affinity Chromatography |
| Synonyms: | MRD5; p135 SynGAP; RASA1; RASA5; SYNGAP1 |
| Background: | Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |