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Syntenin Rabbit Monoclonal Antibody

Cat Number: MABN87790
Conjugate: Unconjugated
Size: 100μL
Clone: Monoclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: A synthetic peptide of human Syntenin
Reactivity: Human
Applications: WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:20-1:50,IP 1:10-1:100
Molecular: Calculated MW:32 kDa; Observed MW:32 kDa
Purification: Affinity Purification
Synonyms: ST1; MDA9; SYCL; MDA-9; TACIP18
Background:

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017]

Form: Liquid
Buffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.