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TGF beta1 R

Cat Number: AB-81203
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Recombinant protein of human TGFBR1.
Reactivity: Hu,Ms
Applications:

Western Blot: 1:500 – 1:2000
Immunohistochemstry: 1:50 – 1:200
Immunofluorescence: 1:50 – 1:200

Molecular: 56kDa
Purification: Aff. Pur.
Synonyms: TGFBR1; AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TGFR-1; tbetaR-I;TBRI; TBR-i; TGF-beta receptor type-1
Background:

The protein encoded by this gene forms a heteromeric complex with type II TGFbeta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene

Form: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
AB-81203-1.jpg

Western blot analysis of extracts of
various cell lines, using TGFBR1
antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-
Rabbit IgG (H+L) at 1:10000
dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in
TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.

AB-81203-2.jpg

Immunofluorescence analysis of
NIH/3T3 cells using TGFBR1 antibody
at dilution of 1:100. Blue:
DAPI for nuclear staining.