Thrombomodulin/CD141 Rabbit Monoclonal Antibody
| Cat Number: | MABN84750 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from mouse Thrombomodulin |
| Reactivity: | Mouse,Rat |
| Applications: | WB 1:1000-1:2000,IHC 1:100-1:200,FC 1:20-1:100 |
| Molecular: | Calculated MW: 62 kDa ; Observed MW: 105,70 kDa |
| Purification: | Affinity Purification |
| Synonyms: | AHUS6; BDCA3; CD141; CD141 antigen; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin; ;Thrombomodulin |
| Background: | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |