TIA1 (2C12) Rabbit Monoclonal Antibody
| Cat Number: | MABN18915 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human TIA1 |
| Reactivity: | Human |
| Applications: | WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500,IP 1:20-1:50 |
| Molecular: | 43kDa |
| Purification: | Affinity purification |
| Synonyms: | Nucleolysin TIA 1 isoform p40; p40 TIA 1; TIA1 protein; TIAL1; TIAR; |
| Background: | Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3′ untranslated regions (3′ UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3′ untranslated regions (3′ UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |