TINF2 Rabbit Monoclonal Antibody
| Cat Number: | MABN03921 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human Tin2 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | WB 1:500-1:1000 |
| Molecular: | Calculated MW:50 kDa;Observed MW: 50 kDa |
| Purification: | Affinity Purification |
| Synonyms: | DKCA3; Tin 2; TIN2; TINF 2; Tinf2 |
| Background: | Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. |
| Form: | Liquid |
| Buffer: | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |