TIRAP Rabbit Monoclonal Antibody
| Cat Number: | MABN84311 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human TIRAP |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000 |
| Molecular: | Calculated MW: 24 kDa ; Observed MW: 28 kDa |
| Purification: | Affinity Purification |
| Synonyms: | MAL; Wyatt;;TIRAP |
| Background: | Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha (TNF) and interleukin-6 (IL6). |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |