TLS/FUS Rabbit Monoclonal Antibody
| Cat Number: | MABN86791 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human TLS/FUS |
| Reactivity: | Human |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,FC 1:50-1:200 |
| Molecular: | Calculated MW:53 kDa; Observed MW:70 kDa |
| Purification: | Affinity Purification |
| Synonyms: | TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2 |
| Background: | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009] |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |