TMEM173 Rabbit Monoclonal Antibody
| Cat Number: | MABN21585 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG,Kappa |
| Immunogen: | Recombinant protein of human STING |
| Reactivity: | Human,Mouse,Rat, |
| Applications: | WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
| Molecular: | CalcuLated MW:42kD;Observed MW:37kD |
| Purification: | Protein A |
| Synonyms: | TMEM173;ERIS;MITA;STING;Transmembrane protein 173;Endoplasmic reticuLum interferon stimuLator;ERIS;Mediator of IRF3 activation;hMITA;StimuLator of interferon genes protein;hSTING |
| Background: | Cell localization:Cytoplasmic, Membranous.This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014], |
| Form: | Liquid |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |