TNF alpha
| Cat Number: | MAB-94636 |
|---|---|
| Size: | 100 ug |
| Clone: | TNF-3 |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human TNF. |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:1000 - 1:2000 Immunohistochemistry: 1:50 - 1:200 Immunofluorescence: 1:50 - 1:200 |
| Molecular Weight: | 17kDa |
| Purification: | Aff. Pur. |
| Synonyms: | TNF;DIF;TNF-alpha;TNFA;TNFSF2;TNLG1F;TNF alpha |
| Background: | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases,including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide,50% glycerol, pH7.3. |