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Transmembrane Protein 30B Rabbit Monoclonal Antibody

Cat Number: MABN02697
Conjugate: Unconjugated
Size: 100μL
Clone: Monoclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human TMEM30B
Reactivity: Human
Applications: WB 1:500-1:1000
Molecular: Calculated MW: 39 kDa; Observed MW: 39 kDa
Purification: Affinity Purification
Synonyms: CDC50B
Background:

Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.

Form: Liquid
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.