TREX1 Rabbit Monoclonal Antibody
| Cat Number: | MABN84253 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human TREX1 |
| Reactivity: | Human |
| Applications: | WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200 |
| Molecular: | 33 kDa |
| Purification: | Affinity Purification |
| Synonyms: | AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1;;TREX1 |
| Background: | Major cellular 3′-to-5′ DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3′ termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |