TRIM24 Rabbit Monoclonal Antibody
| Cat Number: | MABN87041 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human TRIM24 |
| Reactivity: | Human,Mouse |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:200 |
| Molecular: | Calculated MW:117 kDa; Observed MW:117 kDa |
| Purification: | Affinity Purification |
| Synonyms: | PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA |
| Background: | The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains – a RING, a B-box type 1 and a B-box type 2 – and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |