TRIM25 Mouse Monoclonal Antibody
| Cat Number: | MABN81735 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG2b |
| Immunogen: | Purified recombinant fragment of human TRIM25 (AA: 211-360) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:250,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular: | 71kDa |
| Purification: | Affinity Purification |
| Synonyms: | EFP; Z147; RNF147; ZNF147 |
| Background: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |