TriMethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody
| Cat Number: | MABN84830 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic methyl-peptide corresponding to residues surrounding Lys27 of human Histone H3 |
| Reactivity: | Human,Rat |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20 |
| Molecular: | Calculated MW: 15 kDa; Observed MW: 15 kDa |
| Purification: | Affinity Purification |
| Synonyms: | H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a |
| Background: | H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
| Form: | Liquid |
| Buffer: | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |