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TriMethyl-Histone H3 (Lys27) Rabbit Monoclonal Antibody

Cat Number: MABN02834
Conjugate: Unconjugated
Size: 100μL
Clone: Monoclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: A synthetic Methylated peptide corresponding to residues target protein
Reactivity: Human,Rat
Applications: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50,ChIP 1:20
Molecular: Calculated MW: 15 kDa; Observed MW: 15 kDa
Purification: Affinity Purification
Synonyms: H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a
Background:

H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Form: Liquid
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.