U1A Rabbit Monoclonal Antibody
| Cat Number: | MABN84138 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human U1A |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50 |
| Molecular: | 31 kDa |
| Purification: | Affinity Purification |
| Synonyms: | Mud1; snRNP A; SNRPA; U1-A; U1A;;U1A |
| Background: | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5′ splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |