Ubiquitin Conjugating Enzyme E2 N Rabbit Monoclonal Antibody
| Cat Number: | MABN03248 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Ube2N/Ubc13 |
| Reactivity: | Human,Rat |
| Applications: | WB 1:500-1:1000,ICC/IF 1:50-1:200 |
| Molecular: | Calculated MW: 17 kDa; Observed MW: 17 kDa |
| Purification: | Affinity Purification |
| Synonyms: | BLU; HEL-S-71; Ubc13; UbCH ben; UbcH13; UBCHBEN; Ube2n |
| Background: | The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical ‘Lys-63’-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |