Ubiquitin Protein Ligase E3A Rabbit Monoclonal Antibody
| Cat Number: | MABN03249 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human UBE3A |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 |
| Molecular: | Calculated MW: 101 kDa; Observed MW: 101 kDa |
| Purification: | Affinity Purification |
| Synonyms: | Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP; HPVE6A |
| Background: | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |