ULBP1 (3U10) Rabbit Monoclonal Antibody
| Cat Number: | MABN19619 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human ULBP1 |
| Reactivity: | Human |
| Applications: | FC 1:50-1:100 |
| Molecular: | 28kDa |
| Purification: | Affinity purification |
| Synonyms: | Alcan beta; N2DL1; NKG2DL1; RAET1I; UL16; UL16 binding protein 1; ULBP1; |
| Background: | Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |