ULBP2 Mouse Monoclonal Antibody
| Cat Number: | MABN82327 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Immunogen: | Purified recombinant fragment of human ULBP2 (AA: 26-216) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | ICC 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular: | 27.4kDa |
| Purification: | Affinity Purification |
| Synonyms: | N2DL2; RAET1H; RAET1L; NKG2DL2; ALCAN-alpha |
| Background: | This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015] |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |