UPB1 Rabbit Monoclonal Antibody
| Cat Number: | MABN21230 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG,Kappa |
| Immunogen: | A synthetic peptide of human UPB1 |
| Reactivity: | Human |
| Applications: | WB 1:1000-1:5000,IHC 1:100-1:300,IP 1:50-1:100 |
| Molecular: | CalcuLated MW:;Observed MW:42kD |
| Purification: | Protein A |
| Synonyms: | UPB1;BUP1;Beta-ureidopropionase ;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase; |
| Background: | Cell localization:Cytoplasm..This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008] |
| Form: | Liquid |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |