USF1 (Phospho-Thr153) Rabbit Polyclonal Antibody
| Cat Number: | ABN06108 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from human USF1 (Phospho-Thr153) |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000 |
| Molecular: | 34kDa |
| Purification: | Affinity purification |
| Synonyms: | Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1) |
| Background: | disease:Genetic variations in USF1 are associated with combined hyperlipidemia type 1 (HYPLIP1) [MIM:602491]; also known as familial combined hyperlipidemia type 1 (FCHL1). HYPLIP1 is characterized by elevated levels of serum total cholesterol, triglycerides or both, and is observed in about 20% of individuals with premature coronary heart disease.,function:Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5′-CACGTG-3′) that is found in a variety of viral and cellular promoters.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2). Interacts with varicella-zoster virus IE62 protein., |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |