USP13 Rabbit Polyclonal Antibody
| Cat Number: | ABN00260 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human USP13 |
| Reactivity: | Human,Mouse |
| Applications: | WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50 |
| Molecular: | Calculated MW: 97 kDa; Observed MW: 97 kDa |
| Purification: | Affinity Chromatography |
| Synonyms: | Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13 |
| Background: | Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |