VAMP2 Rabbit Polyclonal Antibody
| Cat Number: | ABN00172 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human VAMP2 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50 |
| Molecular: | Calculated MW: 13 kDa; Observed MW: 16 kDa |
| Purification: | Affinity Chromatography |
| Synonyms: | vesicle-associated membrane protein 2 (synaptobrevin 2); SYB2; VAMP-2 |
| Background: | The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |