VCAM1 Rabbit Monoclonal Antibody
| Cat Number: | MABN01575 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of mouse VCAM1 |
| Reactivity: | Mouse |
| Applications: | WB 1:500-1:1000,IP 1:20-1:50 |
| Molecular: | Calculated MW: 81 kDa; Observed MW: 100 kDa |
| Purification: | Affinity Purification |
| Synonyms: | VCAM1; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106 |
| Background: | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |