Vimentin
| Cat Number: | MAB-10362 |
|---|---|
| Size: | 100 ug |
| Clone: | VI-01 |
| Concentration: | 1mg/ml |
| Host: | Ms |
| Isotype: | IgM |
| Immunogen: | beta-site APP-cleaving enzyme 1 |
| Reactivity: | Mamm |
| Applications: | Western Blot: 1:500-1:1000 Immunoprecipitation: 1:500-1:1000 Immunohisotchemistry: 1:100-1:400 |
| Molecular: | 70-75kDa |
| Purification: | Immunogen affinity purified |
| Synonyms: | BACE, KIAA1149 Observed MW: 70-75 kDa |
| Background: | Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
| Storage: | , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |