VPS18 Rabbit Monoclonal Antibody
| Cat Number: | MABN84209 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human VPS18 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100 |
| Molecular: | Calculated MW: 110 kDa ; Observed MW: 100 kDa |
| Purification: | Affinity Purification |
| Synonyms: | hVPS18; PEP3; vps18;;VPS18 |
| Background: | Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |