Top

VPS24 Rabbit Monoclonal Antibody

Cat Number: MABN87794
Conjugate: Unconjugated
Size: 100μL
Clone: Monoclonal
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human VPS24
Reactivity: Human,Mouse,Rat
Applications: WB 1:1000-1:5000,IHC 1:50-1:100,FC 1:10-1:100,IP 1:10-1:100
Molecular: Calculated MW:25 kDa; Observed MW:25 kDa
Purification: Affinity Purification
Synonyms: NEDF; VPS24; CGI-149
Background:

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]

Form: Liquid
Buffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.