WDFY3 Mouse Monoclonal Antibody
| Cat Number: | MABN82306 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Immunogen: | Purified recombinant fragment of human WDFY3 (AA: 3277-3526) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular: | 395kDa |
| Purification: | Affinity Purification |
| Synonyms: | ALFY; BCHS; MCPH18; ZFYVE25 |
| Background: | This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |