WDR5 Rabbit Monoclonal Antibody
| Cat Number: | MABN02772 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human WDR5 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000 |
| Molecular: | Calculated MW: 37 kDa; Observed MW: 37 kDa |
| Purification: | Affinity Purification |
| Synonyms: | WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein |
| Background: | Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at ‘Lys-4’. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3. H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |