WDR5 Rabbit Polyclonal Antibody
| Cat Number: | ABN00274 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human WDR5 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100 |
| Molecular: | Calculated MW: 37 kDa; Observed MW: 37 kDa |
| Purification: | Affinity Chromatography |
| Synonyms: | WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein |
| Background: | Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at ‘Lys-4’. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3. H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |