XBP1 Rabbit Monoclonal antibody
| Cat Number: | MABN03817 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human XBP1 |
| Reactivity: | Human,Mouse |
| Applications: | WB 1:500-1:1000,IP 1:20-1:50 |
| Molecular: | Calculated MW: 29 kDa; Observed MW: 29 kDa |
| Purification: | Affinity Purified |
| Synonyms: | XBP1; TREB5; XBP2; X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5 |
| Background: | Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5′-GATGACGTG[TG]N(3)[AT]T-3′, and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |