xCT Rabbit Monoclonal Antibody
| Cat Number: | MABN83994 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human xCT |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50 |
| Molecular: | 55 kDa |
| Purification: | Affinity Purification |
| Synonyms: | CCBR1; Cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT; ;xCT |
| Background: | Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |