YAP
| Cat Number: | AB-84335 |
|---|---|
| Size: | 100μg |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1. |
| Reactivity: | Hu,Ms,Rt |
| Applications: | Western Blot: 1:500 - 1:2000 Immunohistochemistry: 1:50 - 1:200 Immunofluorescence: 1:50 - 1:200 Immunoprecipitation: 1:20 - 1:50 |
| Molecular Weight: | 72kDa |
| Purification: | Aff. Pur. |
| Synonyms: | COB1;YAP;YAP2;YAP65;YKI;YAP1 |
| Background: | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Form: | Liquid |
| Buffer: | PBS with 0.02%sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/ thaw cycles. |