YAP (Phospho Ser127) Rabbit Monoclonal Antibody
| Cat Number: | MABN21109 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG,Kappa |
| Immunogen: | A synthetic Phosphorylated peptide corresponding to residues target protein |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:2000-1:10000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
| Molecular: | CalcuLated MW:55kD;Observed MW:55kD |
| Purification: | Protein A |
| Synonyms: | YAP1;YAP65;Yorkie homolog;65 kDa Yes-associated protein;YAP65 |
| Background: | Cell localization:Cytoplasm, Nucleus.This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013], |
| Form: | Liquid |
| Buffer: | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |