YAP1 Rabbit Monoclonal Antibody
| Cat Number: | MABN02782 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to target protein |
| Reactivity: | Human |
| Applications: | WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50 |
| Molecular: | Calculated MW: 54 kDa; Observed MW: 65 kDa |
| Purification: | Affinity Purification |
| Synonyms: | YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65 |
| Background: | YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |