Z280B Rabbit Polyclonal Antibody
| Cat Number: | ABN20012 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Reactivity: | Human,Rat,Mouse |
| Applications: | WB 1:500-1:2000,ELISA 1:5000-1:20000 |
| Molecular: | 59kDa |
| Purification: | Affinity purification |
| Background: | The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015],function:May function as a transcription factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 4 C2H2-type zinc fingers., |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |