ZNF420 Rabbit Polyclonal Antibody
| Cat Number: | ABN20264 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Polyclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ZNF420. AA range:301-350 |
| Reactivity: | Human,Mouse |
| Applications: | WB 1:500-1:2000,ELISA 1:20000-1:40000 |
| Molecular: | 80kDa |
| Purification: | Affinity purification |
| Synonyms: | ZNF420; Zinc finger protein 420 |
| Background: | zinc finger protein 420(ZNF420) Homo sapiens The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016],function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 KRAB domain.,similarity:Contains 19 C2H2-type zinc fingers., |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |