Western Blot: 1:1000 – 1:5000
Immunohistochemistry: 1:50 – 1:100
Immunofluorescence: 1:50 – 1:100
Immunocytochemistry: 1:50 – 1:100
Immunoprecipitation: 1:20 – 1:50
ChIP: 1:20 – 1:100

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.