alpha/beta Synuclein Rabbit Monoclonal Antibody
| Cat Number: | MABN86637 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human alpha Synuclein |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:5000,ICC/IF 1:50-1:100,FC 1:20-1:50 |
| Molecular: | 18 kDa |
| Purification: | Affinity purification |
| Synonyms: | PD1; NACP; PARK1; PARK4 |
| Background: | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Western blot analysis of extracts from Mouse brain tissue using alpha/beta Synuclein Rabbit Monoclonal Antibody at 1:1000.