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ASM

Cat Number: AB-J199
Size: 100ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Recombinant protein of human SMPD1 / ASM
Reactivity: Hu, Ms
Applications: Western Blot: 1:500 - 1:2000 Immunofluorescence: 1:50 - 1:100
Molecular Weight: 60kDa
Purification: Aff. Pur.
Synonyms: SMPD1;ASM;ASMASE;NPD;SMPD1/ASM
Background:

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann- Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

Form: Liquid
Buffer: PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.