ASM Rabbit Polyclonal Antibody
| Cat Number: | AB-84383 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | sphingomyelin phosphodiesterase 1, acid lysosomal |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western Blot: 1:500-1:2000 |
| Molecular: | 60kDa |
| Purification: | Immunogen affinity purified |
| Synonyms: | Sphingomyelin phosphodiesterase|Acid sphingomyelinase (aSMase)|Sphingomyelin phosphodiesterase, processed form|SMPD1|ASM |
| Background: | The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann- Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |