Top

ASM Rabbit Polyclonal Antibody

Cat Number: AB-84383
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: sphingomyelin phosphodiesterase 1, acid lysosomal
Reactivity: Human, Mouse, Rat
Applications:

Western Blot:  1:500-1:2000

Molecular Weight: 60kDa
Purification: Immunogen affinity purified
Synonyms: Sphingomyelin phosphodiesterase|Acid sphingomyelinase (aSMase)|Sphingomyelin phosphodiesterase, processed form|SMPD1|ASM
Background:

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann- Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

Form: Liquid
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
AB-84383-1

Mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with ( SMPD1, ASM Antibody) at dilution of 1:300.