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AXL Rabbit Polyclonal Antibody

Cat Number: AB-84768
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from Axl . at AA range: 630-710
Reactivity: Human, Mouse, Rat
Applications:

Western Blot: 1/500 – 1/2000
ELISA: 1/10000.
Molecular Weight: 130kD
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms: AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene
Background:

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two
immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin
K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types.
Alternative splicing results in multiple transcript variants of this gene.
Form: Liquid
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20°C. Avoid repeated freeze-thaw cycles.
AB-84768-1

Western blot analysis of 293T using Axl antibody.
Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000