BCL-2
Cat Number: | AB-81822 |
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Conjugate: | Unconjugated |
Size: | 100 ug |
Clone: | POLY |
Concentration: | 1mg/ml |
Host: | Rb |
Isotype: | IgG |
Immunogen: | Synthesized peptide derived from human Bcl-2 around the nonphosphorylation site of T69. Immunogen Region 20-100 aa. |
Reactivity: | Hu, Ms, Rt |
Applications: | WB: 1:1000-1:2000 |
Molecular Weight: | 26 kDa |
Purification: | Aff. Pur. |
Background: | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release . |
Form: | Liquid |
Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Storage: | Store at -20°C,and avoid repeat freeze-thaw cycles. |

Western Blot (WB) analysis of specific cells using Bcl-2 Polyclonal Antibody.