Catenin gamma / CTNNG1
| Cat Number: | MABX-80096 |
|---|---|
| Size: | 100 ug |
| Clone: | CN-3 |
| Concentration: | 1mg/ml |
| Host: | Ms |
| Isotype: | IgG1 |
| Immunogen: | Recombinant chicken plakoglobin. |
| Reactivity: | Hu, Rt, Ch |
| Applications: | Western blot: 2mug/ml Immunocytochemistry: 1mug/ml Immunohistochemistry(Frozen Section): 4mug/ml |
| Purification: | Purified |
| Background: | Junction Plakoglobin(JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. |
| Form: | Liquid |
| Buffer: | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
| Storage: | At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing. |