CD86 Rabbit Polyclonal Antibody
| Cat Number: | AB-84793 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | CD86 molecule |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western Blot: 1:200-1:2000 Immunohistochemistry: 1:50-1:500 Immunofluorescence: 1:20-1:200 |
| Molecular Weight: | 75 kDa |
| Purification: | Immunogen affinity purified |
| Synonyms: | Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, CTLA 4 counter receptor B7.2, FUN 1, LAB72 |
| Background: | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
| Storage: | Store at -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |